基因与信号

出版时间：2003-8  出版社：清华大学出版社  作者：普坦森  页数：192  

内容概要

我国的生命科学与生物技术和美国、日本等发达国家相比还有较大差距，存在生命科学基础理论研究不够深入扎实、学术创新能力不强、拥有自主知识产权的生物技术产品种类少、产量低、生物技术产业规模小、相关配套产业社会化程度低等问题。为了高等院校师生和广大科技人员借鉴和学习发达国家生命科学与技术的先进理论和技术，提高我国在生物经济方面的竞争力，我们精选了一批国外优秀生命科学与生物技术著作，组织专家进行了评阅和审核，希望能对高等院校师生和广大科技人员有所帮助，同时对我国生命科学和生物技术产业赶超世界先进水平起到一定的推动作用。

书籍目录

PrefaceForewordIntroductionCHAPTER 1 Lessons from Bacteria  RNA POLYMERASE  REGULATED RECRUITMENT:THE/ac GENES    Protein-DNA Interactions    Detecting Physiological Signals    promoter Recognition and Transcription by RNA Polymerase    Switching the Genes On:Activation by CAP      Cooperative Binding of Proteins to DNA      Cooperative Binding and Gene Activation by CAP    Repression by Lac Repressor    Interim Summary and Extension  MORE REGULATED RECRUITMENT:THE BACTERIOPHAGE     The Switch    Establishing Lysogeny    Analogies with lac      promoters       Protein-DNA interactions      Repression      Activation      Detecting Physiological Signals    Making an Efficient Switch      Cooperative Binding of  Repressor to DNA      Autogenous Control by Repressor  PANEL:Antitermination:N and Q    Interim Summary and Extensions      Activation :A Closer Look      DNA binding:A Closer Look      Synergy  POLYMERASE ACTIVATION:glnA AND RELATED GENES    Promoter Recognition by  containing Ploymerase    DNA Binding by NtrC    Detecing the Physiological Signal    Activation by NtrC    Other Activatjors of Polymerase    Interim Summary  PANEL:Phage T4 Late Genes  PROMOTER ACTIVATION:merT AND RELATED GENES    Promoter Recognition    Detection the Physiological and Activation    Interim Summary  GENERAL SUMMARY  PANEL:more on Repression in Bacteria  FOOTNOTES  BIBLIOGRAPHYCHAPTER 2 Yeast:A single-celled Eukaryote……CHAPTER 3 Some Note on Higher EukaryotesCHAPTER 4 Enyme Specificity and RegulationAfterwordAppendicesAppendix1:More on CooperativityApperdix2:Topogenic SepuencesAppendix3:All-or-none Effects and Levels of Gene ExpressionIndex