毒理学百科

出版时间:2007-10  出版社:科学  作者:威克斯勒 编  页数:553  
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内容概要

本书为毒理学医学类百科全书,主要包含了毒理学的重要概念,如计量效应、作用机制、试验程序、靶位等,还收集了与毒理学相关的历史、法律、条例、数据库。对毒理学家会相当有用,同时也适用于医学、法律、科学工作者查阅。    本书是在原版Encyclopedia of Toxicology(2nd edn)的基础上对词条进行的分类重排。编成三卷,分别为精选卷、拓展卷与社科管理卷,更加适合国内读者阅读。本书涵盖了毒理学研究的各个领域,从基础到前沿,甚至一些尚存争议的问题也包含其中。     第二版百科全书汇集了392作者提供的1057条目录,而第一版只包括200名作者提供的749条目录。实际上,第一版中所有条目的内容在第二版中都得到了充实,而某些条目则完全进行了更新。在第二版中新出现的308个条目中,包括鸟类生态毒理学、基准剂量、杀虫剂、计算机毒理学、致癌效力因素、代谢组学、化学事件、蒙地卡罗分析、非致死性化学武器、无脊椎动物生态毒理学、药物滥用、癌症化疗因子和消费产品等等。许多针对特殊化学物的条目都是全新的,而书中搜录的国际组织也得到了很大的扩展。某些条目罗列了许多著名的毒物中毒相关事件:如美国拉夫运河事件、泰晤士海滩事件、切尔诺贝利事件和三里岛事件等。另外许多条目涉及毒理学知识的社会应用,如文化毒理学、环境犯罪、著名投毒者和中毒可件、古代化学生物战以及美国环境运动历史等。因此,新版的毒理学百科全书在长度、广度、以及深度上都对毒理学的许多方面进行了更广泛和深入的概述。

作者简介

作者:(美国)威克斯勒

书籍目录

Aberrations of Chromosomes(染色体畸变,染色体异常)see Chromosome AberrationsAbsorption(吸收)Jules Brodeur and Robert TardifAcceptable Daily Intake(ADI)(每日允许摄入量)Jaya Chilakapati and Harihara M MehendaleAggregate Exposures(累积照射)Jeffrey H DriverAmes Test(埃姆斯试验)Robin C GuyAnalytical Toxicology(分析毒理学)Shayne C GadAneuploidy(非整倍性)David A EastrnondAnimal Models(动物模型)Shayne C GadAquatic Ecotoxicology(水域生态毒理学、水域生态毒物学)see EcotoxicologyAquaticAquatic Toxicity Testing(水生毒性试验)see Toxicity Testing,AquaticAvian Ecotoxicology(鸟类生态毒理学)see Ecotoxicology,AvianBehavioral Toxicity Testing(行为中毒试验、行为毒性试验)see Toxicity Testing BehavioralBehavioral Toxicology(行为毒理学)Deborah A Cory-SlechtaBenchmark Dose(基准剂量)Qiyu Jay ZhaoBiological Exposure Index(生物照射)Alan J WeinrichBiomarkers,Environmental(环境生物标记),Lee R ShugartBiomarkers,Human Health(人类健康生物标记)Rogene F HendersonBiotrans{ormation(生物转化)Tanya C McCarthy and Christopher J SinaiCarcinogen-DNA Adduct Formation and DNA Repair(致癌原一DNA加合物形成与DNA修复)Ainsley Weston andMiriam C PoirierCarcinogenesis(致癌作用)David E Malarkey and Robert R MaronpotCarcinogenicity Toxicity Testing(致癌毒性试验)see Toxicity Testing Carcinog-enesisChemical-Specific Adjustment Factor(CSAF)(化学特异性调节因子)Bette MeekChromosome Aberrations(染色体畸变、染色体异常)Antone L BrooksCombustion Toxicology(燃烧毒理学)Barbara C Levin and Erica D Kul igowskiCommon Mechanism of Toxicity(主要毒性机理)Beth MilesonComputational Toxicology(计算机毒理学)S Satheesh Anand and Harihara M Meh-endaleCumulative Risk Assessment(累积危险评价)Jeffrey H DriverDeoxyribonucleic Acid(脱氧核糖核酸)see Aneuploidy;Carcinogen-DNA AdductFormation and DNA Repair;Chromosome Aberrations;DNA Phosphoramidites;Genetic Toxicology;Genomics.ToxicogenomicsDernlal Toxicity Testing(皮肤毒性试验)see Toxicity Testing,DermalDevelopment Toxicity Testing(发育毒性试验)see Toxicity Testing,DevelopmentalDevelopmental Toxicology(发育毒理学)Calvin C Willhite and Philip E MirkesDNA(脱氧核糖核酸)see Aneuploidy;Carcinogen-DNA Adduct Formation andDNA Repair;Chromosome Aberrations;DNA Phosphoramidites;Genetic To-xicology;Genonlics,Toxicogenomics;Molecular Toxicology~Recombinant DNATechnology Toxicity Testing.MutagenicityDNA Adduct(DNA加合物)see Carcinogen-DNA Adduct Formation and DNA RepairDNA Phosphoramidites(DNA亚磷酰胺)Sang-Tae KimDNA Repair(DNA修复)see Carcinogen-DNA Adduct Formation and DNA RepairDominant Lethal Tests(显性致死试验)Samantha E GadDose-Response Relationship(剂量效应关系)Samantha E GadEcotoxicology(生态毒理学、生态毒物学)Chris TheodorakisEcotoxicology,Aquatic(水域生态毒理学)Yuan Zhao and Michael C NewmanEcotoxicology,Avian(-g类生态毒理学)Pierre Mineau1Ecotoxicology,Genetic(遗传生态毒理学)Wendy L Rose and Susan L AndersonEcotoxicology,Invertebrate(无脊椎动物生态毒理学)Pawel J MigulaEcotoxicology,Terrestrial(陆地生物生态毒理学)Anne Fairbrother and Bruce HopeEcotoxicology,Wildlife(野生动植物生态毒理学)Richard S HalbrookEnvironmental Hormone Disruptors(环境激素破坏剂)Lorenz Rhomberg and MaraSeeleyEnvironmental Toxicology(环境毒理学)Chris TheodorakisExposure(暴露)Gary Whitmyre and Sam KacewExposure Assessment[(危害)暴露评估]Gary Whitmyre and Jeffrey H DriverExposure Criteria(暴露标准)Andrew MaierEye Irritancy Testing(眼球刺激试验)Samantha E GadFood Safety and Toxicology(食品安全与毒理学)Michael Bolger and Clark D Carr_ingtonForeign Body Response(异物反应)Shayne C GadForensic Toxicology(法医毒理学)Felix K AdatsiGenetic Ecotoxicology(遗传生态毒理学)see Eeotoxicology,GeneticGenetic Toxicology(遗传毒理学)Joseph R LandolphGenomics,Toxicogenomics(基因组、毒物基因组)Kartik Shankar and Harihara M MehendaleGOOd Clinical Practice(GcP)(药物临床试验管理规范)Sharmilee P Sawant and Harihara M MehendaleGood LaboratorY Practices(GLP)(良好实验室管理规范)Robin C GuyHormesis(毒物刺激作用)Elyisha A Hanniman and Christopher J SinaiHormone Disruptors(激素破坏剂)see Environmental Hormone DisruptorsHost-Mediated Assay(宿主间介试验)David A EastmondHypersensitivity,Delayed Type(迟发型超敏反应)Leigh Ann Burns-NaasImmediately Dangerous to Life or Health(IDLH)Values(即刻性损伤或致死浓度) Alan J WeinrichInhalation Testing(吸入试验)see Toxicity Testing,InhalationInteractions(相互作用)see Interactive ToxicityInteractive Toxicity(相互作用毒性)S Satheesh Anand and Harihara M MehendaleIrritation Testing(刺激试验)see Toxicity Testing,IrritationLD50/LCs0(Lethal Dosage 50/Lethal Concentration 50)(半数致死剂量)Shayne C GadLethal,Dosage Or Concentration(致死剂量/浓度)see LD50/LC50(Lethal Dosage50/Lethal Concentration 50)Levels of Effect in Toxicological Assessment(毒物效应评价水平)Michael DoursonLowest-Observed~Adverse-Effect Level(观察到副作用的最小剂量)see Levels ofEffect in Toxicological AssessmentLowest-Observed-Effect Level(观察到作用的最小剂量,最低作用水平)see Leve-Is of Effect in Toxicological AssessmentMargin of Exposure(MOE)(暴露界限)Udayan M Apte and Harihara M MehendaleMaximum Allowable Concentration(MAC)(最高容许浓度)Shayne C GadMaximum T01erated Dose(MTD)(最大耐受剂量)Shayne C GadMechanisms of Toxicity(毒性机制)Sanjay Chanda and Harihara M MehendaleMode of Action(作用方式)Lynne HaberModels(模型)see Animal ModelsModifying Factors of Toxicity(毒性修饰因子)Frank C Lu and Sam KacewM01ecular Toxic010gy_Recombinant DNA Technology(分子毒理学一重组DNA技术)Evan A ThackaberryMouse Lymphoma Assay(小鼠淋巴瘤测定)Robin C GuyNeoplasia(瘤形成)see CarcinogenesisNeurotoxicity(神经毒性)Peter S Spencer and Pamela J LeinNonionizing Radiation(非电离辐射)see Radiation Toxicology,Ionizing and Non-ionizingNo-Observed-Adverse-Effect Level(未观察到的副作用水平)see Levels of Effectin Toxicological AssessmentNo-Observed-ElfeCt Level(未观察到的效应水平)see Levels of Effect in Toxicol-ogical AssessmentOccupational Exposure Limits(职业性暴露极限)Andrew MaierOccupational Toxicology(职业毒理学)Elizabeth V Wattenberg3Ototoxicity(耳毒性)Michael J SullivanPharmacokinetiCS/Toxicokinetics(药物代谢动力学/毒物代谢动力学)Robert Tardifand Jules BrodeurPharmacology and Safety(安全药理学)see Safety Pharmacology(拓展卷)Radiation Toxicology,Ionizing and Nonionizing(电离辐射与非电离辐射毒理学)Bobby R Scott and Raymond A GuilmetteRecombinant DNA(重组DNA)see Molecular Toxicology-Recombinant DNA Tee-hnologySafety Testing,Clinical Studies(临床研究安全试验)Alessandra Pagnoni366Sensitivity Analysis(灵敏度分析)Virginia LauSensitization Testing(敏感试验、致敏试验)see Toxicity Testing,SensitizationShort-Term Exposure Limit(短期暴露限度)see Occupational Exposure LimitsSubchronic Toxicity(亚慢性毒性)see Toxicity,SubchronicTeratology(畸形学)see Developmental ToxicologyTeratology Testing(致畸实验)see Toxicity Testing,DevelopmentalTerrestrial Ecotoxicology(陆地生态毒理学)see Ecotoxicology,TerrestrialThreshold Limit Value(阈限值)see Occupational Exposure LimitsToxicity Testing,Alternatives(选择性毒性试验)Shayne C GadToxicity Testing,Aquatic(水域毒性试验)Shayne C GadToxicity Testing,Behavioral(行为毒性试验)Samantha E GadToxicity Testing,Carcinogenesis(致癌毒性试验)Shayne O GadToxicity Testing,Dermal(皮肤毒性试验)Samantha E Gad and Shayne C GadToxicity Testing,Developmental(发育毒性试验)Rochelle W TylToxicity Testing,Inhalation(吸人毒性试验)Samantha E Gad and Shayne C GadToxicity Testing,Irritation(刺激毒性试验)Pertti J HakkinenToxicity Testing,Modeling(模型化毒性试验)Charles A Pittinger,Andrew Worth,Joanna Jaworska and Joanne ShatkinToxicity Testing,Mutagenicity(致突变毒性试验)Robin C Guy435Toxicity Testing,'Read Across Analysis'[识读交叉分析(毒性试验)]Pertti JHakkinenToxicity Testing,Reproductive(生殖毒性试验)Rochelle W TylToxicity Testing,Sensitization(致敏毒性试验)Rob in C GuyToxicity Testing,Validation(毒性试验验证)Leon H Bruner,G J Carr,M Chamb-erlain and R D CurrenToxicity,Acute(急性毒性)Donald J EcobichonToxicity,Chronic(长期毒性)Donald J EcobichonToxicity,Subchronic(亚慢性毒性)Donald J EcobichonToxicokinetics(毒物代谢动力学)see Pharmacokinetics/ToxicokineticsToxicology(毒理学)Gabriel L PlaaToxicology,Intuitive(直觉毒理学)Pertti J HakkinenUncertainty Analysis(不确定检验)Virginia LauUncertainty Factors(不确定系数)Michael DoursonValidation of Toxicity Testing(毒性试验验证)see Toxicity Testing,ValidationVeterinary Toxicology(兽医毒理学)Wilson K Rumbeiha and Frederick W OehmeVirtually Safe Dose(VSD)(实际安全剂量)Stephen M DiZio拓展卷目录社科管理卷目录未收录词条

编辑推荐

  本书在原版Encyclopedia ofToxicology(2nd edn)的基础上对词条进行了分类重排.编成三卷.分别为精选卷、拓展卷与社科管理卷.更加适合国内读者阅读。本书涵盖了毒理学研究的各个领域,从基础到前沿,甚至一些尚存争议的问题也包含其中。

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用户评论 (总计2条)

 
 

  •   这套全英文的百科书涉及毒理学的方方面面,很详细,很全面,具有特别重要的意义,对于从事毒理学研究的科研人员很有价值.而且还列出了参考文献,这对于想进一步拓展了解或研究的人员也有提示作用.但是,本书的导读内容太少,起不到引导读者进一步深入阅读的作用,称为"导读版"似乎有点言过其实.
  •   对于英语水平一般的人读起来会有点吃力。这个内容是毒理学基础,但是英文又让人比较难懂,对于英语国家的毒理学初学者比较好。但是对国内毒理学初学者又比较难
 

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