分子生物学

出版时间：1999-3  出版社：科学出版社  作者：特纳  页数：346  
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内容概要

　　“精要速览系列(Instant Notes Series)”是国外教材“Best Seller”榜的上榜教材。该系列结构新颖，视角独特；重点明确，脉络分明；图表简明清晰；英文自然易懂，被国内多所重点院校选用作为双语教材。先锋版是继“现代生物学精要速览”之后推出的跨学科的升级版本。　　本书是该系列中的《分子生物学(第二版)》分册，全书共19章。新版在原版的基础上内容进行了全面调整和扩充，增加了若干新专题，如中心法则、细胞周期和细胞凋亡等，书后并附有练习题。　　本书是指导大学生快速掌握分子生物学基础知识的优秀教材，也是辅助教师授课的极佳教学参考书，同时可供生命科学相关专业的研究生参考。

书籍目录

AbbreviationsPreface to the second editionPreface to the first editionSection A-Cells and macromoleculesA1 Cellular classificationA2 Subcellular organellesA3 MacromoleculesA4 Large macromolecular assembliesSection B-Protein structureB1 Amino acidsB2 Protein structure and functionB3 Protein anslysisSection C-Properties of nucleic acidsC1 Nucleic acid structureC2 Chemical and physical properties of nucleic acidsC3 Spectroscopic and thermal properties of nucleic acidsC4 DNA supercoilingSection D-Prodaryotic and eukaryotic chromosome structureD1 Prokaryotic chromosome structureD2 Chromatin structureD3 Eukaryotic chromosome structureD4 Genome complexityD5 The flow of genetic informationSection E-DNA replicationE1 DAN replication:an overviewE2 Bacterial DNA replicationE3 The cell cycleE4 Eukaryotic DNA replicationSection F-DNA damage,repair and recombinationF1 MutagenesisF2 DNA damageF3 DNA repairF4 RecombinationSection G-Gene manipulationG1 DNA cloning:an overviewG2 Preparation of plasmid DNAG3 Restriction enzymes and electrophoresisG4 Ligation,transformation and analysis of recombinantsSection H-Cloning vectorsH1 Design of plasmid vectorsH2 Bacteriophage vectorsH3 Cosmids,YACs and BACsH4 Eukaryotic vectorsSection I-Gene libraries and scrreeningI1 Genomic librariesI2 cDNA librariesI3 Screening proceduresSection J-Analysis and uses of cloned DNAJ1 Characterization of clonesJ2 Nucleic acid sequencingJ3 Polymerase chain reactionJ4 Organization of cloned genesJ5 Mutagenesis of cloned genesJ6 Applications of cloningSection K-Transcription in prokaryotesK1 Basic principles of transcriptionK2 Escherichia coli RNA polymeraseK3 The E.coliσpromoterK4 Transcription,initiation,elongation and terminationSection L-Regulation of transcription in prokaryotesL1 The lac operonL2 The trp operonL3 Transcriptional regualation by alternative σfactorsSection M-Transcription in eukaryotesM1 The three RNA polymerases:characterization and functionM2 RNA Pol Ⅰ genes:the ribosomal repeatM3 RNA Pol Ⅲ genes:5S and tRNA transcriptionM4 RNA Pol Ⅱ genes:promoters and enhancersM5 General transcription factors and RNA Pol Ⅱ initiationSection N-Regulation of transcription in eukaryotesN1 Eukaryotic transcription factorsN2 Examples of transcriptional regulationSection O-RNA processing and RNPsO1 rRNA processing and ribosomesO2 tRNA processing,RNase P and ribozymesO3 mRNA processing,hnRNPs and snRNPsO4 Alternative mRNA processingSection P-The genetic code and tRNAP1 The genetic codeP2 tRNA structure and functionSection Q-Protein synthesisQ1 Aspects of protein synthesisQ2 Mechanism of protein synthesisQ3 Initiation in eukaryotesQ4 Translational control and post-translational evenrtsSection R-Bacteriophages and eukaryotic virusesR1 Introduction to virusesR2 BacteriophagesR3 DNA virusesR4 RNA virusesSection S-Tumor viruses and oncogenesS1 Oncogenes found in tumor virusesS2 Categories of oncogenesS3 Tumor suppressor genesS4 ApoptosisFurther readingMultiple choice questionsAnswersIndex